Condensates compartmentalizing proteins and nucleic acids are often the location of dysregulation in cancer, and the pharmocodynamics of cancer therapeutics can be affected by condensates.
We deploy our live-cell super-resolution technology to determine the interaction of lead compounds and condensate components in intact cells. Our imaging at high-frequency and over extended durations gives us unparalleled input data for our machine learning algorithms, meaning novel insight into hit discovery, hit-to-lead, target identification, mode of action and lead optimization.
High-frequency image capture rates
Extended durations: minutes, hours, even days
Without damage or artifacts unlike other super-res systems = Ultra-rich protein behavior data for AI analysis
Unprecedented platform for discovery
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